Pome-Bio Prebiotic (60 capsules)

Understanding Prebiotics

Prebiotics help nourish beneficial gut bacteria such as lactobacilli and bifidobacteria. Common prebiotics include inulin, fructooligosaccharides, and galactooligosaccharides. Foods that naturally contain prebiotic compounds include garlic, onions, leeks, asparagus, seaweed, burdock root, flaxseed, konjac, apples, unripe bananas, beans, almonds, and whole grain oats. Including prebiotic compounds in the diet can help support a balanced intestinal environment.

Potential Benefits of Prebiotics

• Supports a Balanced Intestinal Environment:

Prebiotics help nourish beneficial bacteria and support a diverse gut microbiome.

• Supports Digestive Wellness:

Prebiotics may help support digestive regularity and overall digestive comfort.

• Supports Beneficial Bacterial Activity:

Beneficial bacteria can metabolize prebiotic compounds into short-chain fatty acids that are associated with normal gut function.

• Supports Nutritional Utilization:

A balanced gut environment may help support normal digestion and nutrient utilization as part of a healthy diet.

• Supports Satiety and Healthy Eating Habits:

Prebiotic-rich diets may help support fullness and balanced eating patterns.

Considerations with Traditional Fiber-Based Prebiotics

Some fiber-based prebiotics, such as inulin, fructooligosaccharides, and galactooligosaccharides, may cause temporary gas or bloating in sensitive individuals. For those looking for a different approach, polyphenol-based prebiotic ingredients may offer an alternative way to support the gut microbiome.

Polyphenol-Based Prebiotics

Polyphenols, including compounds found in pomegranate and citrus fruits, are being studied for their ability to interact with the gut microbiome. Ingredients such as punicalagin from pomegranate and citrus bioflavonoids like hesperidin and naringin may help support beneficial bacteria and a balanced intestinal environment. Including more polyphenol-rich foods in the diet can be a practical way to support overall digestive wellness.

Pome-Bio Prebiotic Ingredients

[Pomanox® Pomegranate Fruit Extract]

Pomanox® is a pomegranate fruit extract that contains naturally occurring polyphenols such as ellagic acid and punicalagin. These compounds provide antioxidant support and help support overall wellness. Research also suggests that pomegranate polyphenols may help support the growth of beneficial intestinal microorganisms. When these compounds reach the lower digestive tract, they can be metabolized by gut bacteria into compounds such as urolithin.

[Urolithin-Related Research]

• Mitochondrial Support:

Urolithin has been studied for its role in supporting healthy cellular function, including mitochondrial quality control.

• Healthy Aging Support:

Preliminary research has explored the relationship between urolithin and healthy aging processes.

• Muscle Wellness Support:

Early-stage research has examined how urolithin may help support normal muscle function as part of healthy aging.

[Pomegranate and Beauty Nutrition]

Pomegranate is valued for its naturally occurring antioxidants, vitamins, and plant compounds. These nutrients help support overall wellness and can be a valuable part of a beauty-focused nutrition routine.

• Antioxidant Support:

Pomegranate contains antioxidant compounds such as ellagic acid and punicalagin that help protect against oxidative stress.

• Skin Hydration Support:

Pomegranate naturally contains compounds that are often included in beauty-focused nutrition for skin wellness support.

• Hair Wellness Support:

Pomegranate provides naturally occurring nutrients that can complement a balanced beauty and wellness routine.

[MicrobiomeX® Citrus Bioflavonoid Complex]

MicrobiomeX® is a citrus bioflavonoid complex designed to support gut microbiome health. Polyphenols from citrus fruits may interact with beneficial bacteria and help support the production of short-chain fatty acids associated with normal intestinal function. Research has also explored how citrus bioflavonoids may support digestive wellness and a balanced gut environment.

Pome-Bio Prebiotic's Unique Formulation

Pome-Bio Prebiotic combines Pomanox® and MicrobiomeX® to provide plant-based support for the gut microbiome, digestive comfort, antioxidant balance, and everyday wellness. This formula offers an alternative approach to prebiotic support using polyphenol-rich ingredients from pomegranate and citrus.

• Pomanox® Pomegranate Fruit Extract

The patented Pomanox® is sourced from Euromed in Spain and is produced from fresh pomegranate fruit harvested under controlled conditions for consistent quality. Its Pure-Hydro™ process uses water-based technology to create a high-quality extract without harsh chemical solvents. Pomanox® is standardized for punicalagins, key pomegranate polyphenols studied for antioxidant and microbiome support.

• MicrobiomeX® Citrus Bioflavonoid Complex

Developed by BioActor in the Netherlands, MicrobiomeX® is a specialized complex of citrus bioflavonoids including hesperidin and naringin. These compounds have been studied for their role in supporting a balanced gut environment and beneficial bacterial activity.

• Quality Assurance and Safety

Pome-Bio Prebiotic is manufactured in the USA in a facility that follows strict quality control procedures and safety standards. The product undergoes testing for identity, purity, stability, and overall quality. Third-party lot testing is also used to help ensure raw material and finished product quality.

Made in USA.

Suggested Use

Take 2 capsules daily, or as directed by your healthcare professional.

Ingredients

Serving Size: 2 Capsules

• Calories 5
• Total Carbohydrate 1 g
• Dietary Fiber, less than 1 g
• Pomegranate Fruit Extract (Pomanox®) [Standardized to contain 30% Total Punicalagins (A & B) and Punicalins (A & B)] 500 mg
• Citrus Bioflavonoid Complex (MicrobiomeX®) 500 mg

Other ingredients: Microcrystalline Cellulose, Hypromellose (Natural Vegetable Capsules), Magnesium Stearate, Silicon Dioxide

* Contains no: Eggs, dairy products, animal products, corn, soy, fish, crustaceans, nuts, peanuts, flour, gluten, sugar, yeast, artificial colors, or flavors.

Dr. Ozawa makes supplements with a strong focus on quality and safety. Products that do not meet strict inspection standards for raw materials and finished goods are not released for shipment. As a result, manufacturing may occasionally be delayed. We appreciate your understanding.

References

Euromed Nature & Science. In vitro Studies on the Bifidogenic effect of Pomanox. Bialonska D, Ramnani P, Kasimsetty SG, Muntha KR, Gibson GR, Ferreira D. The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota. Int J Food Microbiol. 2010;140(2-3):175-182. Li Z, Henning SM, Lee RP, et al. Pomegranate extract induces ellagitannin metabolite formation and changes stool microbiota in healthy volunteers. Food Funct. 2015;6(8):2487-2495. Makki K, Deehan EC, Walter J, Bäckhed F. The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease. Cell Host Microbe. 2018;23(6):705-715. Duda-Chodak A, Tarko T, Satora P, Sroka P. Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review. Eur J Nutr. 2015;54(3):325-341. Stevens Y, Rymenant EV, Grootaert C, et al. The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients. 2019;11(7).

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.